The Cross-Border Biotech Blog

Biotechnology, Health and Business in Canada, the United States and Worldwide

Monthly Archives: December 2011

Friday Science Review: December 30, 2011

Hedgehog Signaling Upholds Integrity of BBB University of Montreal ♦ Published in Science, December 23, 2011 The blood-brain barrier (BBB) is a crucial boundary within the body that restricts the migration of blood-borne molecules and immune cells from circulation into the brain. Specialized endothelial cells tightly bound together with junctional proteins ensure that only certain small [...]

Friday Science Review: December 23, 2011

Super-Selective Oncolytic Virus Ottawa Hospital Research Institute ♦ Published in Molecular Therapy (npg), December 20, 2011 More on oncolytic viruses this week but not with VSV this time, but rather the poxvirus JX-594. This particular virus, while having an excellent therapeutic index against multiple solid tumour types, is not that well understood. Researchers seeking to understand the [...]

Friday Science Review: December 16, 2011

Homeostasis in the Gut, Plasma Cells on Patrol University of Toronto ♦  McGill University ♦ University of Bern ♦ Memorial University of Newfoundland Published in Nature, December 11, 2011 The intestine is the largest mucosal surface in the body and is exposed to a diversity of microbes. This microbial life is healthy, although the immune system must still [...]

Monday Biotech Deal Review: December 12, 2011

Welcome to your Monday Biotech Deal Review for December 12, 2011.  Microbix and PharmaGap each completed private placements, together raising over $1 million.  As well, Nuvo Research is purchasing the minority interest in its German subsidiary from Dr. Friedrich-Wilherm Kuehne.  Read on to learn more. 

Friday Science Review: December 9, 2011

hiPSC-derived HSCs Engraft Mouse Model McMaster Stem Cell and Cancer Research Institute ♦ Published in Stem Cells, November 30, 2011 There are several sources currently being used to isolate hematopoietic stem cells (HSCs) for transplantation in humans. Included in these are the bone marrow, peripheral blood, and umbilical cord blood. However, HSCs derived from human embryonic [...]

Monday Biotech Deal Review: December 5, 2011

Welcome to your Monday Biotech Deal Review for December 5, 2011.  Some equity investment activity occurred over the previous week, with Resverlogix closing its previously announced $17.5M private placement, Response Biomedical announcing an $8M rights offering, and various other small private placements.  As well, Valeant is going to fund its acquisition of iNova with debt, [...]

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